Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.

Package	Per pill	Price	Savings
180 tablet	BGN 1.34	BGN 241.50BGN 1.34	BGN 426.97
120 tablet	BGN 1.55	BGN 185.75BGN 1.55	BGN 259.90
90 tablet	BGN 1.86	BGN 167.16BGN 1.86	BGN 167.07
60 tablet	BGN 2.32	BGN 139.29BGN 2.32	BGN 83.54
30 tablet	BGN 3.71	BGN 111.41BGN 3.71

Package	Per pill	Price	Savings
120 tablet Free AirMail shipping Hot	BGN 8.52	BGN 1022.03BGN 8.52	BGN 185.47
90 tablet Free AirMail shipping Hot	BGN 8.98	BGN 808.31BGN 8.98	BGN 97.31
60 tablet Free AirMail shipping Hot	BGN 9.29	BGN 557.43BGN 9.29	BGN 46.32
36 tablet Free AirMail shipping Hot	BGN 9.81	BGN 353.00BGN 9.81	BGN 9.25
24 tablet	BGN 10.06	BGN 241.50BGN 10.06

Package	Per pill	Price	Savings
90 tablet Free AirMail shipping Hot	BGN 10.32	BGN 929.11BGN 10.32	BGN 185.58
60 tablet Free AirMail shipping Hot	BGN 11.15	BGN 668.93BGN 11.15	BGN 74.20
36 tablet Free AirMail shipping Hot	BGN 11.87	BGN 427.34BGN 11.87	BGN 18.54
24 tablet Free AirMail shipping Hot	BGN 12.39	BGN 297.25BGN 12.39

Brand(s)

Defnalone

Manufacturer

Lupin

Disease(s)

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

Hypersensitivity to deflazacort;
Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
Gastrointestinal Perforation: GI disorders;
Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
Effects on Bones: decreases in bone mineral density;
Serious Skin Rashes;
Ophthalmic Effects: May include cataracts, infections, and glaucoma;
Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.

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