Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.

Package	Per pill	Price	Savings
180 tablet	BGN 1.37	BGN 246.83BGN 1.37	BGN 436.39
120 tablet	BGN 1.58	BGN 189.85BGN 1.58	BGN 265.63
90 tablet	BGN 1.90	BGN 170.85BGN 1.90	BGN 170.76
60 tablet	BGN 2.37	BGN 142.36BGN 2.37	BGN 85.38
30 tablet	BGN 3.80	BGN 113.87BGN 3.80

Package	Per pill	Price	Savings
120 tablet Free AirMail shipping Hot	BGN 8.70	BGN 1044.58BGN 8.70	BGN 189.56
90 tablet Free AirMail shipping Hot	BGN 9.18	BGN 826.14BGN 9.18	BGN 99.46
60 tablet Free AirMail shipping Hot	BGN 9.50	BGN 569.73BGN 9.50	BGN 47.34
36 tablet Free AirMail shipping Hot	BGN 10.02	BGN 360.79BGN 10.02	BGN 9.45
24 tablet	BGN 10.28	BGN 246.83BGN 10.28

Package	Per pill	Price	Savings
90 tablet Free AirMail shipping Hot	BGN 10.55	BGN 949.61BGN 10.55	BGN 189.68
60 tablet Free AirMail shipping Hot	BGN 11.39	BGN 683.69BGN 11.39	BGN 75.83
36 tablet Free AirMail shipping Hot	BGN 12.13	BGN 436.77BGN 12.13	BGN 18.95
24 tablet Free AirMail shipping Hot	BGN 12.66	BGN 303.81BGN 12.66

Brand(s)

Defnalone

Manufacturer

Lupin

Disease(s)

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

Hypersensitivity to deflazacort;
Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
Gastrointestinal Perforation: GI disorders;
Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
Effects on Bones: decreases in bone mineral density;
Serious Skin Rashes;
Ophthalmic Effects: May include cataracts, infections, and glaucoma;
Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.

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