Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.

Package	Per pill	Price	Savings
180 tablet	£ 0.54	£ 97.74£ 0.54	£ 172.79
120 tablet	£ 0.63	£ 75.17£ 0.63	£ 105.18
90 tablet	£ 0.75	£ 67.65£ 0.75	£ 67.61
60 tablet	£ 0.94	£ 56.37£ 0.94	£ 33.81
30 tablet	£ 1.50	£ 45.09£ 1.50

Package	Per pill	Price	Savings
120 tablet Free AirMail shipping Hot	£ 3.45	£ 413.62£ 3.45	£ 75.06
90 tablet Free AirMail shipping Hot	£ 3.63	£ 327.13£ 3.63	£ 39.38
60 tablet Free AirMail shipping Hot	£ 3.76	£ 225.59£ 3.76	£ 18.75
36 tablet Free AirMail shipping Hot	£ 3.97	£ 142.86£ 3.97	£ 3.74
24 tablet	£ 4.07	£ 97.74£ 4.07

Package	Per pill	Price	Savings
90 tablet Free AirMail shipping Hot	£ 4.18	£ 376.01£ 4.18	£ 75.11
60 tablet Free AirMail shipping Hot	£ 4.51	£ 270.72£ 4.51	£ 30.03
36 tablet Free AirMail shipping Hot	£ 4.80	£ 172.95£ 4.80	£ 7.50
24 tablet Free AirMail shipping Hot	£ 5.01	£ 120.30£ 5.01

Brand(s)

Defnalone

Manufacturer

Lupin

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

Hypersensitivity to deflazacort;
Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
Gastrointestinal Perforation: GI disorders;
Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
Effects on Bones: decreases in bone mineral density;
Serious Skin Rashes;
Ophthalmic Effects: May include cataracts, infections, and glaucoma;
Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.

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