Emflaza

Deflazacort

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.

Package	Per pill	Price	Savings
180 tablet	£ 0.56	£ 100.49£ 0.56	£ 177.67
120 tablet	£ 0.64	£ 77.29£ 0.64	£ 108.15
90 tablet	£ 0.77	£ 69.56£ 0.77	£ 69.52
60 tablet	£ 0.97	£ 57.96£ 0.97	£ 34.76
30 tablet	£ 1.55	£ 46.36£ 1.55

Package	Per pill	Price	Savings
120 tablet Free AirMail shipping Hot	£ 3.54	£ 425.28£ 3.54	£ 77.18
90 tablet Free AirMail shipping Hot	£ 3.74	£ 336.35£ 3.74	£ 40.49
60 tablet Free AirMail shipping Hot	£ 3.87	£ 231.95£ 3.87	£ 19.27
36 tablet Free AirMail shipping Hot	£ 4.08	£ 146.89£ 4.08	£ 3.85
24 tablet	£ 4.19	£ 100.49£ 4.19

Package	Per pill	Price	Savings
90 tablet Free AirMail shipping Hot	£ 4.30	£ 386.61£ 4.30	£ 77.22
60 tablet Free AirMail shipping Hot	£ 4.64	£ 278.35£ 4.64	£ 30.87
36 tablet Free AirMail shipping Hot	£ 4.94	£ 177.82£ 4.94	£ 7.71
24 tablet Free AirMail shipping Hot	£ 5.15	£ 123.69£ 5.15

Brand(s)

Defnalone

Manufacturer

Lupin

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

Hypersensitivity to deflazacort;
Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
Gastrointestinal Perforation: GI disorders;
Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
Effects on Bones: decreases in bone mineral density;
Serious Skin Rashes;
Ophthalmic Effects: May include cataracts, infections, and glaucoma;
Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.

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